Cancer immunotherapy and toxic epidermal necrolysisCancer immunotherapy and toxic epidermal necrolysis

Cancer immunotherapy and toxic epidermal necrolysis

Immunotherapy has come to play an increasingly important role in cancer treatment. Accordingly, immune-related adverse events (irAEs) have drawn considerable attention. In this case, a young female patient developed immune-related toxic epidermal necrolysis (TEN). The same irAEs have been rarely reported in previous studies. In this study, we describe the treatment and care methods used …

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Effect of nutritional interventions on discharged older patients: study protocol for a randomized controlled trial

Effect of nutritional interventions on discharged older patients: study protocol for a randomized controlled trial

During hospitalization, many older sufferers are at dietal danger or malnourished, and their dietal situation is usually additional impaired throughout hospitalization. After discharge, a “diet hole” typically happens during which the affected person doesn’t obtain sufficient diet to make sure an optimum restoration.The study is a randomized controlled study ongoing over 112 days. At discharge, the intervention group receives steerage …

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Peripheral blood markers predictive of outcome and immune-related adverse events in advanced non-small cell lung cancer treated with PD-1 inhibitors.

Peripheral blood markers predictive of outcome and immune-related adverse events in advanced non-small cell lung cancer treated with PD-1 inhibitors.

Selected sufferers with advanced non-small cell lung cancer (NSCLC) profit from immunotherapy, particularly immune checkpoint inhibitors resembling PD-1 (programmed cell loss of life protein 1) inhibitor. Peripheral blood biomarkers can be most handy to foretell therapy outcome and immune-related adverse events (irAEs) in candidate sufferers. This examine explored associations between inflammation-related peripheral blood markers and …

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Risk and reward: extending stochastic glycaemic control intervals to reduce workload

Risk and reward: extending stochastic glycaemic control intervals to reduce workload

STAR is a model-based, personalised, risk-based dosing strategy for glycaemic control (GC) in critically unwell sufferers. STAR gives secure, efficient control to practically all sufferers, utilizing 1-Three hourly measurement and intervention intervals. However, the typical 11-12 measurements per day required could be a medical burden in lots of intensive care items. This research goals to considerably reduce …

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Ethical Dilemmas at the Beginning and End of Life: A Needs-Based, Experience-Informed, Small-Group, Case-Based Curriculum for Pediatric Resident

Ethical Dilemmas at the Beginning and End of Life: A Needs-Based, Experience-Informed, Small-Group, Case-Based Curriculum for Pediatric Resident

Pediatric residents are confronted with moral dilemmas in beginning- and end-of-life conditions all through their coaching. These conditions are innately difficult, but regardless of suggestions that residents obtain coaching in ethics and end-of-life domains, they proceed to report the want for further coaching. To tackle these considerations, we developed an interactive and reflective palliative care …

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